MicroRNAs are a class of small noncoding RNAs (20-22 nucleotides). MicroRNAs regulate gene expression by directly binding gene's 3'-UTR regions. Many studies reveal that miRNAs play roles in tumorigenesis. MiR-26a plays different roles in different types of cancer, and participates in tumor growth, invasion, metastasis, angiogenesis, metabolism, diagnosis and prognosis. This review summarizes the progress of miR-26a study in cancer.
微小RNA（microRNAs, miRNAs）是一类由20个-22个核苷酸组成的小片段非编码RNA，通过靶向结合基因mRNA的3’非翻译区（3’-UTR）调控其表达。许多研究报道miRNAs参与肿瘤的发生发展。MiR-26a在不同的肿瘤中发挥不同的作用，在肿瘤增殖、转移侵袭、血管形成、生物代谢及诊断预后中都有作用。本文就miR-26a与肿瘤关系的研究进展进行综述。.
Keywords: Target genes; Tumors; miR-26a.