Nucleolar Condensation: A New Mechanism to Control Mitotic Exit

Andrés Clemente-Blanco

doi:10.1016/j.cub.2017.10.016

Nucleolar Condensation: A New Mechanism to Control Mitotic Exit

Curr Biol. 2017 Nov 20;27(22):R1220-R1222. doi: 10.1016/j.cub.2017.10.016.

Author

Andrés Clemente-Blanco¹

Affiliation

¹ Cell Cycle and Genome Stability Group, Instituto de Biología Funcional y Genómica. Consejo Superior de Investigaciones Científicas (CSIC), Universidad de Salamanca (USAL), Salamanca, Spain. Electronic address: andresclemente@usal.es.

PMID: 29161561
DOI: 10.1016/j.cub.2017.10.016

Abstract

The nucleolus in Saccharomyces cerevisiae is one of the last genomic regions to be condensed in mitosis. A new study shows that this extended nucleolar relaxation state is fundamental for the timely execution of mitotic exit.

Publication types

Comment

MeSH terms

Cell Cycle Proteins / genetics
Cell Nucleolus
DNA, Ribosomal
Mitosis
Protein Tyrosine Phosphatases
Saccharomyces cerevisiae Proteins / genetics*

Substances

Cell Cycle Proteins
DNA, Ribosomal
Saccharomyces cerevisiae Proteins
Protein Tyrosine Phosphatases