Crystal structure of (1 R,5 S)- endo-(8-methyl-8-azoniabi-cyclo-[3.2.1]oct-3-yl)ammonium aqua-tri-chlorido-nitratocopper(II)

Sergey N Britvin; Andrey M Rumyantsev

doi:10.1107/S2056989017014633

Crystal structure of (1 R,5 S)- endo-(8-methyl-8-azoniabi-cyclo-[3.2.1]oct-3-yl)ammonium aqua-tri-chlorido-nitratocopper(II)

Acta Crystallogr E Crystallogr Commun. 2017 Oct 20;73(Pt 11):1712-1715. doi: 10.1107/S2056989017014633. eCollection 2017 Nov 1.

Authors

Sergey N Britvin¹, Andrey M Rumyantsev²

Affiliations

¹ Department of Crystallography, Saint Petersburg State University, Universitetskaya Nab. 7/9, 199034 St Petersburg, Russian Federation.
² Department of Genetics and Biotechnology, Saint Petersburg State University, Universitetskaya Nab. 7/9, 199034 St Petersburg, Russian Federation.

Abstract

The structure of a salt of diprotonated endo-3-amino-tropane crystallized with a copper(II) anionic cluster is reported, viz. (C₈H₁₈N₂)[CuCl₃(NO₃)(H₂O)]. Neither ion in the salt has been structurally characterized previously. In the crystal, the ions pack together to form a three-dimensional structure held together by a network of inter-molecular N-H⋯O, O-H⋯Cl and N-H⋯Cl hydrogen-bonding inter-actions. Selective crystallization of the title compound can be considered as a simple method for the separation of the exo and endo isomers of 3-amino-tropane.

Keywords: copper(II)complex; crystal structure; isomer separation; nitrogen heterocycle; tropane.

Grants and funding

This work was funded by Saint-Petersburg State University grants 0.37.235.2015 and 3.37.222.2015.