Towards 'off-the-shelf' genetically modified T cells: prolonging functional engraftment in mice by CD8 veto T cells

Leukemia. 2018 Apr;32(4):1039-1041. doi: 10.1038/leu.2017.332. Epub 2017 Nov 20.

Authors

N Or-Geva¹, R Gidron-Budovsky¹, L Radomir¹, Y Edelstein¹, A K Singh¹, R Sidlik-Muskatel¹, E Ophir¹, E Bachar-Lustig¹, Y Reisner¹

Affiliation

¹ Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.

PMID: 29151584
DOI: 10.1038/leu.2017.332

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
CD8-Positive T-Lymphocytes / immunology*
Female
Immune Tolerance / genetics
Immune Tolerance / immunology
Immunologic Memory / genetics*
Immunologic Memory / immunology
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, Nude
Mice, Transgenic
Neoplasms / genetics
Neoplasms / immunology
Receptors, Antigen, T-Cell / genetics
Receptors, Antigen, T-Cell / immunology
Receptors, Chimeric Antigen / genetics
Receptors, Chimeric Antigen / immunology

Substances

Receptors, Antigen, T-Cell
Receptors, Chimeric Antigen