Annual banned-substance review: Analytical approaches in human sports drug testing

Drug Test Anal. 2018 Jan;10(1):9-27. doi: 10.1002/dta.2336. Epub 2017 Dec 18.

Abstract

Several high-profile revelations concerning anti-doping rule violations over the past 12 months have outlined the importance of tackling prevailing challenges and reducing the limitations of the current anti-doping system. At this time, the necessity to enhance, expand, and improve analytical test methods in response to the substances outlined in the World Anti-Doping Agency's (WADA) Prohibited List represents an increasingly crucial task for modern sports drug-testing programs. The ability to improve analytical testing methods often relies on the expedient application of novel information regarding superior target analytes for sports drug-testing assays, drug elimination profiles, alternative test matrices, together with recent advances in instrumental developments. This annual banned-substance review evaluates literature published between October 2016 and September 2017 offering an in-depth evaluation of developments in these arenas and their potential application to substances reported in WADA's 2017 Prohibited List.

Keywords: doping; mass spectrometry; meldonium; sport.

Publication types

  • Review

MeSH terms

  • Doping in Sports / legislation & jurisprudence
  • Doping in Sports / prevention & control*
  • Humans
  • Performance-Enhancing Substances / analysis*
  • Performance-Enhancing Substances / blood
  • Performance-Enhancing Substances / chemistry*
  • Substance Abuse Detection / legislation & jurisprudence
  • Substance Abuse Detection / methods*

Substances

  • Performance-Enhancing Substances