Porcine Astrovirus Type 3 in Central Nervous System of Swine with Polioencephalomyelitis

Abstract

Using next-generation sequencing, we identified and genetically characterized a porcine astrovirus type 3 strain found in tissues from the central nervous system of 1 piglet and 3 sows with neurologic signs and nonsuppurative polioencephalomyelitis. Further studies are needed to understand the potential for cross-species transmission and clinical impact.

Keywords: Mamastrovirus; Sus scrofa; astrovirus; central nervous system; high-throughput nucleotide sequencing; meningitis/encephalitis; neurologic disease; pigs; polioencephalomyelitis; swine; viruses; zoonoses.