In Vivo Validation of a Less Invasive Gastrostimulator

Artif Organs. 2017 Nov;41(11):E213-E221. doi: 10.1111/aor.13056.

Abstract

Gastrointestinal stimulator implants have recently shown promising results in helping obese patients lose weight. However, to place the implant, the patient currently needs to undergo an invasive surgical procedure. We report a less invasive procedure to stimulate the stomach with a gastrostimulator. After attempting fully endoscopic implantation, we more recently focused on a single incision percutaneous procedure. In both cases, the challenges in electronic design of the implant are largely similar. This article covers the work achieved to meet these and details the in vivo validation of a gastrostimulator aimed to be endoscopically placed and anchored to the stomach.

Keywords: -Design and implementation; -Gastric electrical stimulation; -Implanted gastric stimulator; -In vivo validation; Obesity.

Publication types

  • Validation Study

MeSH terms

  • Animals
  • Appetite Regulation*
  • Dogs
  • Eating*
  • Electric Stimulation Therapy / instrumentation*
  • Electric Stimulation Therapy / methods
  • Electromyography
  • Equipment Design
  • Feeding Behavior*
  • Gastroscopy
  • Implantable Neurostimulators*
  • Male
  • Materials Testing
  • Models, Animal
  • Prosthesis Implantation / instrumentation*
  • Prosthesis Implantation / methods
  • Stomach / innervation*
  • Time Factors