Hydrogen peroxide (H2O2): a review of its use in surgery

Wien Med Wochenschr. 2019 Jun;169(9-10):222-225. doi: 10.1007/s10354-017-0610-2. Epub 2017 Nov 16.

Abstract

Hydrogen peroxide has been used in medicine for more than 100 years. It is known in surgery as a highly useful irrigation solution by virtue of both its hemostatic and its antimicrobial effects. Due to its possible negative effect on wound healing and its cytotoxic effect in higher concentrations, there are concerns about the safety of its use. The objective of this paper is to review the safety and beneficial effects of hydrogen peroxide.

Keywords: Antimicrobial; Cytotoxicity; Hydrogen peroxide; Irrigation solution; Wound healing.

Publication types

  • Review

MeSH terms

  • Humans
  • Hydrogen Peroxide / adverse effects*
  • Hydrogen Peroxide / pharmacology*
  • Surgical Procedures, Operative
  • Wound Healing* / drug effects

Substances

  • Hydrogen Peroxide