Robotic stereotactic treatment for malignant metastasis of solid tumour in the pancreas: A multiple case report and review of literature

Abstract

Metastatic involvement of the pancreas occurs in 5% of patients affected by advanced malignancies. Surgical resection has been reported by number of authors as a valuable option to improve disease control, in particular in patients with limited disease burden and favourable histotypes; however, the benefit of this procedure has been questioned due to patient selection, technical challenges and relevant risk of perioperative mortality and severe complications. In the present study, a cohort of surgically unfit patients affected by a solitary metastasis in the pancreas from various primary tumours received stereotactic radiotherapy with an ablative dose schedule, obtaining promising local and distant disease progression-free delay with minor toxicity. This is the first report to our knowledge on the use of ablative stereotactic radiotherapy of metastasis in the pancreatic gland.

Keywords: Image-guided radiotherapy; Intrapancreatic metastasis; Maladie Oligométastatique; Métastases intrapancréatiques; Oligometastatic disease; Oncologie; Oncology; Radiothérapie guidée par l’imagerie; Radiothérapie stéréotaxique; Stereotactic radiotherapy.