Telomerase reverse transcriptase promoter hypermethylation is associated with metastatic disease in abdominal paraganglioma

Clin Endocrinol (Oxf). 2018 Feb;88(2):343-345. doi: 10.1111/cen.13513. Epub 2017 Nov 27.

Authors

Fredrika Svahn¹, C Christofer Juhlin¹, Johan O Paulsson¹, Omid Fotouhi¹, Jan Zedenius^{2

3}, Catharina Larsson¹, Adam Stenman¹

Affiliations

¹ Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital, CCK, Stockholm, Sweden.
² Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
³ Department of Breast and Endocrine Surgery, Karolinska University Hospital, Stockholm, Sweden.

PMID: 29130501
DOI: 10.1111/cen.13513

No abstract available

Publication types

Letter

MeSH terms

Basic Helix-Loop-Helix Transcription Factors / genetics
DNA Methylation / genetics
DNA Methylation / physiology*
Humans
Membrane Proteins / genetics
Paraganglioma / enzymology*
Paraganglioma / genetics*
Promoter Regions, Genetic / genetics*
Proto-Oncogene Proteins p21(ras) / genetics
Succinate Dehydrogenase / genetics
Telomerase / genetics*

Substances

Basic Helix-Loop-Helix Transcription Factors
Membrane Proteins
TMEM127 protein, human
endothelial PAS domain-containing protein 1
SDHB protein, human
Succinate Dehydrogenase
Telomerase
HRAS protein, human
Proto-Oncogene Proteins p21(ras)