Eosinophilic Esophagitis in Children and Adults

Gastrointest Endosc Clin N Am. 2018 Jan;28(1):59-75. doi: 10.1016/j.giec.2017.07.004.

Abstract

Adults and children with eosinophilic esophagitis (EoE) have distinct clinical and endoscopic presentations. Recognition of clinical signs, along with laboratory and endoscopic findings, is critical for the identification of patients with EoE because delay in diagnosis has been associated with esophageal remodeling and stricture formation. Clinical presentation varies considerably between adults and children. This is less due to differences in the disease and more due to patient differences. This article describes the similarities and differences in clinical presentation of children and adults with EoE, including areas of epidemiology, clinical and endoscopic presentation, pathophysiology, and treatment.

Keywords: Adults; Children; Clinical features; Diet therapy; Dilation; Eosinophilic esophagitis; Treatment.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adrenal Cortex Hormones / therapeutic use
  • Adult
  • Child
  • Child, Preschool
  • Deglutition Disorders / etiology
  • Diet Therapy
  • Eosinophilic Esophagitis / diagnosis*
  • Eosinophilic Esophagitis / epidemiology
  • Eosinophilic Esophagitis / pathology
  • Eosinophilic Esophagitis / therapy*
  • Esophagus / pathology*
  • Fibrosis
  • Food, Formulated
  • Humans
  • Infant
  • Infant, Newborn
  • Symptom Assessment

Substances

  • Adrenal Cortex Hormones