Medical management of pediatric inflammatory bowel disease

Semin Pediatr Surg. 2017 Dec;26(6):360-366. doi: 10.1053/j.sempedsurg.2017.10.005. Epub 2017 Oct 5.

Abstract

Inflammatory bowel diseases (IBD) are chronic autoimmune conditions of the gut affecting both pediatric and adult patients. Medical therapy is often successful at inducing and maintaining remission and preventing disease complications. The mainstays of treatment are medications and other therapies that reduce inflammation and suppress the overactive immune system. Here we review current medical therapies for pediatric IBD, discuss future therapeutics, and present current treatment goals and approaches.

Keywords: Crohn’s disease; Inflammatory bowel disease; Management; Pediatric; Ulcerative colitis.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use*
  • Child
  • Colitis, Ulcerative / drug therapy*
  • Combined Modality Therapy
  • Crohn Disease / therapy*
  • Diet Therapy*
  • Enteral Nutrition*
  • Humans
  • Immunosuppressive Agents / therapeutic use*

Substances

  • Anti-Inflammatory Agents
  • Immunosuppressive Agents

Supplementary concepts

  • Pediatric Crohn's disease
  • Pediatric ulcerative colitis