Laparoscopic Versus Open Restorative Proctocolectomy for Familial Adenomatous Polyposis

J Laparoendosc Adv Surg Tech A. 2018 Jan;28(1):47-52. doi: 10.1089/lap.2017.0397. Epub 2017 Nov 10.

Abstract

Purpose: This study compared outcomes after laparoscopic (LAP) or conventional (open) total proctocolectomy with outcomes after ileal J-pouch anal anastomosis (IPAA) at a single institution.

Methods: Charts from 133 familial adenomatous polyposis patients (1997-2013) were reviewed. Demographic data (age, sex, color, American Society of Anesthesiologists [ASA] status, previous surgery, and body mass index) and surgical outcomes (length of stay, early and late morbidity, reoperation, and mortality rates) were compared among 63 patients undergoing IPAA.

Results: Demographic features were similar among patients (25 open and 38 LAP). Conversely, colorectal cancer at diagnosis prevailed in the open group (60% versus 31.6%; P = .02). Tumor stages (P = .65) and previous surgery index (20% versus 10.5%; P = .46) were similar. Surgical length was longer for LAP (374 versus 281 minutes, P = .003). Short-term complication rates (28% versus 28.9%), hospital stay (10.9 versus 8.9 days), and total long-term reoperations (28% versus 21%) were not statistically different. However, major late morbidity (16% versus 2.6%; P < .001) and late reoperation rates (16% versus 5.2%; P < .05) were greater among open patients. Both groups did not differ regarding pouch failure rates (8% versus 5.2%). There was no operative mortality in the present series.

Conclusions: (1) LAP IPAA is a safe procedure associated with a low conversion rate, (2) short-term results showed no clear advantages for both approaches, and (3) a greater risk of major late complications and late reoperations should be expected after open procedures.

Keywords: familial adenomatous polyposis; ileal pouch anal anastomosis; laparoscopy; postoperative complications; restorative proctocolectomy.

Publication types

  • Comparative Study

MeSH terms

  • Adenomatous Polyposis Coli / diagnosis
  • Adenomatous Polyposis Coli / pathology
  • Adenomatous Polyposis Coli / surgery*
  • Adolescent
  • Adult
  • Anal Canal / surgery*
  • Anastomosis, Surgical / methods
  • Colonic Pouches* / adverse effects
  • Female
  • Humans
  • Ileum / surgery*
  • Laparoscopy / methods*
  • Length of Stay
  • Male
  • Middle Aged
  • Operative Time
  • Postoperative Complications / etiology
  • Proctocolectomy, Restorative / adverse effects
  • Proctocolectomy, Restorative / methods*
  • Reoperation
  • Young Adult