Acute renal artery infarction secondary to dysfibrinogenemia

BMJ Case Rep. 2017 Nov 8:2017:bcr2017221375. doi: 10.1136/bcr-2017-221375.

Abstract

Renal infarction is a rare occurrence accounting for 0.007% of patients seen in the emergency department for renal insufficiency or hypertension. Dysfibrinogenemia is also rare, and the combination of renal artery infarct in the setting of congenital dysfibrinogenemia has not been described in the literature. Our patient, with a remote history of congenital dysfibrinogenemia with no known haemorrhagic or thrombotic complications, presented with acute flank pain and was subsequently diagnosed with an acute renal arterial infarction. He was treated with subcutaneous enoxaparin and then transitioned to lifelong anticoagulation with rivaroxaban therapy.

Keywords: haematology (incl blood transfusion); renal medicine.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Afibrinogenemia / complications
  • Afibrinogenemia / diagnosis*
  • Afibrinogenemia / drug therapy
  • Anticoagulants / therapeutic use
  • Computed Tomography Angiography
  • Diagnosis, Differential
  • Enoxaparin / administration & dosage
  • Enoxaparin / therapeutic use
  • Factor Xa Inhibitors / therapeutic use
  • Flank Pain / diagnosis
  • Flank Pain / diagnostic imaging*
  • Flank Pain / etiology
  • Humans
  • Infarction / drug therapy
  • Infarction / etiology
  • Infarction / pathology*
  • Injections, Subcutaneous
  • Kidney / blood supply*
  • Kidney / pathology
  • Male
  • Rare Diseases
  • Renal Artery / diagnostic imaging
  • Renal Artery / pathology*
  • Rivaroxaban / therapeutic use
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Anticoagulants
  • Enoxaparin
  • Factor Xa Inhibitors
  • Rivaroxaban

Supplementary concepts

  • Dysfibrinogenemia, Congenital