Whole-Genome Sequencing of Lactobacillus Species from Two Commercial Probiotic Products

Anna Colavecchio; Victoria Leo; Sophia Zaccheo; Julie Jeukens; Jean-Guillaume Emond-Rheault; Jérémie Hamel; Irena Kukavica-Ibrulj; Roger C Levesque; Lawrence Goodridge

doi:10.1128/genomeA.01279-17

Whole-Genome Sequencing of Lactobacillus Species from Two Commercial Probiotic Products

Genome Announc. 2017 Nov 9;5(45):e01279-17. doi: 10.1128/genomeA.01279-17.

Authors

Anna Colavecchio¹, Victoria Leo¹, Sophia Zaccheo¹, Julie Jeukens², Jean-Guillaume Emond-Rheault², Jérémie Hamel², Irena Kukavica-Ibrulj², Roger C Levesque², Lawrence Goodridge³

Affiliations

¹ Department of Food Science and Agricultural Chemistry, Food Safety and Quality Program, McGill University, Québec, Canada.
² Institut de Biologie Intégrative et des Systèmes (IBIS), Université Laval, Québec, Québec, Canada.
³ Department of Food Science and Agricultural Chemistry, Food Safety and Quality Program, McGill University, Québec, Canada lawrence.goodridge@mcgill.ca.

Abstract

Eight Lactobacillus strains, each intrinsically resistant to an antibiotic, were isolated from two commercial probiotic products. Whole-genome sequencing identified two efflux transporters, a multidrug and extrusion protein (MATE) efflux transporter, and LmrCD, which may contribute to their intrinsic antibiotic resistance and may therefore facilitate their survival in the intestinal microbiota following antibiotic therapy.