Long noncoding RNA identification in lymphoma

Future Oncol. 2017 Nov;13(27):2479-2487. doi: 10.2217/fon-2017-0230. Epub 2017 Nov 10.

Abstract

It has been found that long noncoding RNA (lncRNA) are abnormally expressed in lymphoma and play an important role in its pathogenesis. Through the detection and analysis of lncRNA, it was found that lncRNA could be used as an excellent biomarker for the diagnosis and prognosis of cancer. In lymphoma, abnormal lncRNA expression is associated with the patient's clinical characteristics, it can be used to determine the prognosis of the patient and serve as a therapeutic target in the disease.

Keywords: biomarkers; diagnosis; lncRNA; lymphoma; prognosis; therapeutic targets.

Publication types

  • Review

MeSH terms

  • Animals
  • Biomarkers, Tumor*
  • Gene Expression Profiling
  • Gene Expression Regulation, Neoplastic*
  • Humans
  • Lymphoma / diagnosis
  • Lymphoma / genetics*
  • Lymphoma / mortality
  • Lymphoma / therapy
  • Molecular Targeted Therapy
  • Prognosis
  • RNA Interference
  • RNA, Long Noncoding / genetics*

Substances

  • Biomarkers, Tumor
  • RNA, Long Noncoding