Antiphospholipid antibody syndrome: The difficulties of diagnosis

JAAPA. 2017 Dec;30(12):10-14. doi: 10.1097/01.JAA.0000526771.67820.59.

Abstract

Antiphospholipid antibody syndrome (APS) is an autoantibody-mediated thrombophilic disorder that causes a hypercoagulable state and can lead to venous thromboembolism, stroke, multiple miscarriages, and other pregnancy complications with the presence of antiphospholipid antibodies. This article reviews screening, diagnosis, and management of APS with a focus on the prevention of long-term complications.

Publication types

  • Review

MeSH terms

  • Adult
  • Antibodies, Antiphospholipid / blood
  • Antibodies, Antiphospholipid / immunology
  • Antiphospholipid Syndrome / diagnosis*
  • Antiphospholipid Syndrome / immunology
  • Antiphospholipid Syndrome / therapy
  • Child
  • Diagnosis, Differential
  • Disease Management
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pregnancy
  • Pregnancy Complications / immunology
  • Venous Thromboembolism / immunology

Substances

  • Antibodies, Antiphospholipid