Electrophysiological Investigations in Orthostatic Myoclonus: Preliminary Findings

Can J Neurol Sci. 2018 Jan;45(1):100-103. doi: 10.1017/cjn.2017.241. Epub 2017 Nov 7.

Abstract

We report the clinical and electrophysiological findings in seven patients with orthostatic myoclonus (OM) associated with gait initiation failure and falls. OM is one of the causes of unsteadiness of stance and gait, and it may develop as a symptom of neurodegenerative disorders. Both positive myoclonic bursts and negative myoclonus may be seen in electrophysiological recordings, and electrophysiological analysis suggests a subcortical origin for OM.

Keywords: Brainstem reflexes; Gait ignition failure; Orthostatic myoclonus; Unsteadiness.

MeSH terms

  • Acoustic Stimulation
  • Aged
  • Aged, 80 and over
  • Blinking / physiology
  • Electromyography / methods*
  • Evoked Potentials, Motor / physiology
  • Female
  • Gait Disorders, Neurologic / diagnosis*
  • Gait Disorders, Neurologic / etiology*
  • Humans
  • Male
  • Myoclonus / complications*
  • Reaction Time
  • Reflex, Startle / physiology
  • Retrospective Studies
  • Severity of Illness Index