Two new flavonol glycosides, limocitrin 3-O-β-D-xylopyranosyl(1→2)-β-D-glucopyranoside (1) and limocitrin 3-O[2-O-β-D-xylopyranosyl-6-O-α-L-rhamnopyranosyl]-β-D-glucopyranoside (2), together with eight known analogs (3-10), were isolated from the fruits of Evodia rutaecarpa. Their structures were elucidated on the basis of spectroscopic analyses and chemical evidences. Meanwhile, Nrf2 inducing abilities of seven isolated compounds were evaluated, and compounds 1, 2, 6, 7, and 8 exhibited moderate effect on Nrf2.
Keywords: Evodia rutaecarpa; Nrf2; Rutaceae; flavonol glycosides.