Anticancer activity of seaweeds

Drug Discov Today. 2018 Feb;23(2):434-447. doi: 10.1016/j.drudis.2017.10.019. Epub 2017 Oct 26.

Abstract

Cancer is a major health problem worldwide and still lacks fully effective treatments. Therefore, alternative therapies, using natural products, have been proposed. Marine algae are an important component of the marine environment, with high biodiversity, and contain a huge number of functional compounds, including terpenes, polyphenols, phlorotannins, and polysaccharides, among others. These compounds have complex structures that have shown several biological activities, including anticancer activity, using in vitro and in vivo models. Moreover, seaweed-derived compounds target important molecules that regulate cancer processes. Here, we review our current understanding of the anticancer activity of seaweeds.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents / pharmacology*
  • Antineoplastic Agents / therapeutic use*
  • Humans
  • Neoplasms / drug therapy*
  • Polyphenols / pharmacology
  • Polyphenols / therapeutic use
  • Polysaccharides / pharmacology
  • Polysaccharides / therapeutic use
  • Seaweed / chemistry*
  • Tannins / pharmacology
  • Tannins / therapeutic use
  • Terpenes / pharmacology
  • Terpenes / therapeutic use

Substances

  • Antineoplastic Agents
  • Polyphenols
  • Polysaccharides
  • Tannins
  • Terpenes