[Clinical trials and perspectives of radiotherapy for uterine endometrial cancers]

Abstract

The adjuvant management of uterine endometrial cancer has been studied in many randomized trials, leading to define postoperative therapeutic indications, depending on the risk factors for relapse, and on the expected benefit in terms of locoregional control and survival. The potential toxicity of treatments should be also considered. We review the available literature that yielded to guidelines that were recently published, on behalf of European societies, and we highlight the perspectives on ongoing studies, aimed at better defining the place and type of adjuvant treatment.

Keywords: Adjuvant treatments; Brachytherapy; Cancers de l’endomètre; Clinical trials; Curiethérapie; Essais cliniques; External beam radiotherapy; Radiothérapie externe; Traitements adjuvants; Uterine endometrial carcinoma.