Hierarchical supramolecular hydrogels: self-assembly by peptides and photo-controlled release via host-guest interaction

Chem Commun (Camb). 2017 Nov 16;53(92):12450-12453. doi: 10.1039/c7cc07859e.

Abstract

A hierarchical supramolecular hydrogel was self-assembled from a Fmoc-RGDS tetrapeptide and showed photo-controlled release directed by host-guest interaction. Multiple payloads, including vesicles, were successively released from a single peptide hydrogel.

MeSH terms

  • Azo Compounds / chemistry
  • Azo Compounds / radiation effects
  • Cyclodextrins / chemistry*
  • Cyclodextrins / radiation effects
  • Drug Liberation
  • Fluorescein-5-isothiocyanate / chemistry
  • Fluorescent Dyes / chemistry
  • Hydrogels / chemistry*
  • Hydrogels / radiation effects
  • Hydrophobic and Hydrophilic Interactions
  • Isomerism
  • Oligopeptides / chemistry*
  • Oligopeptides / radiation effects
  • Viscosity

Substances

  • Azo Compounds
  • Cyclodextrins
  • Fluorescent Dyes
  • Hydrogels
  • Oligopeptides
  • Fluorescein-5-isothiocyanate