DNase1 Does Not Appear to Play a Major Role in the Fragmentation of Plasma DNA in a Knockout Mouse Model

Timothy H T Cheng; Kathy O Lui; Xianlu Laura Peng; Suk Hang Cheng; Peiyong Jiang; K C Allen Chan; Rossa W K Chiu; Y M Dennis Lo

doi:10.1373/clinchem.2017.280446

DNase1 Does Not Appear to Play a Major Role in the Fragmentation of Plasma DNA in a Knockout Mouse Model

Clin Chem. 2018 Feb;64(2):406-408. doi: 10.1373/clinchem.2017.280446. Epub 2017 Nov 2.

Authors

Timothy H T Cheng^{1

2}, Kathy O Lui^{1

2}, Xianlu Laura Peng^{1

2}, Suk Hang Cheng^{1

2}, Peiyong Jiang^{1

2}, K C Allen Chan^{1

2}, Rossa W K Chiu^{1

2}, Y M Dennis Lo^{3

2}

Affiliations

¹ Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories Hong Kong SAR, China.
² Department of Chemical Pathology The Chinese University of Hong Kong Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China.
³ Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, New Territories Hong Kong SAR, China loym@cuhk.edu.hk.

PMID: 29097509
DOI: 10.1373/clinchem.2017.280446

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell-Free Nucleic Acids / blood*
DNA Fragmentation*
Deoxyribonuclease I / metabolism*
Mice
Mice, Knockout

Substances

Cell-Free Nucleic Acids
Deoxyribonuclease I