Lung cancer and chronic obstructive pulmonary disease (COPD) are both serious threats to human health, resulting in a heavy economic burden for the society. Epidemiological studies have shown that lung cancer and COPD have a high comorbid rate. Cigarette smoking is a congenerous risk factor for both lung cancer and COPD, and may lead to these diseases by triggering certain similar pathways. The common pathogenesis of lung cancer and chronic obstructive pulmonary disease involves premature pulmonary failure, oxidative stress and inflammation, telomere length, genetic susceptibility, and epigenetics.
肺癌和慢性阻塞性肺病都是严重威胁人类健康的疾病，给社会带来了沉重的经济学负担。流行病学调查显示肺癌和慢性阻塞性肺病具有高共病率。吸烟是二者共同的危险因素，其可能通过某些共同的通路引起疾病的发生。肺癌和慢性阻塞性肺病的共同发病机制涉及肺部早衰、氧化应激和炎症、端粒长短、基因易感性及表观遗传学。.