Cancer of the Anal Canal: Diagnosis, Staging and Follow-Up with MRI

Korean J Radiol. 2017 Nov-Dec;18(6):946-956. doi: 10.3348/kjr.2017.18.6.946. Epub 2017 Sep 21.

Abstract

Although a rare disease, anal cancer is increasingly being diagnosed in patients with risk factors, mainly anal infection with the human papilloma virus. Magnetic resonance imaging (MRI) with external phased-array coils is recommended as the imaging modality of choice to grade anal cancers and to evaluate the response assessment after chemoradiotherapy, with a high contrast and good anatomic resolution of the anal canal. MRI provides a performant evaluation of size, extent and signal characteristics of the anal tumor before and after treatment, as well as lymph node involvement and extension to the adjacent organs. MRI is also particularly helpful in the assessment of complications after treatment, and in the diagnosis for relapse of the diseases.

Keywords: Anal cancer; Anus; Diagnosis; Magnetic resonance imaging; Staging.

Publication types

  • Review

MeSH terms

  • Aged
  • Anal Canal / anatomy & histology
  • Anal Canal / diagnostic imaging*
  • Anal Canal / pathology
  • Antimetabolites, Antineoplastic / therapeutic use
  • Anus Neoplasms / diagnosis*
  • Anus Neoplasms / diagnostic imaging
  • Anus Neoplasms / pathology
  • Anus Neoplasms / therapy
  • Female
  • Fluorouracil / therapeutic use
  • Follow-Up Studies
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local
  • Neoplasm Staging
  • Positron Emission Tomography Computed Tomography
  • Radiation, Ionizing
  • Tomography, X-Ray Computed

Substances

  • Antimetabolites, Antineoplastic
  • Fluorouracil