Outpatient post-partum antibiotic prescription: method of identification of infection control areas demanding improvements and verification of sensitivity of infection registration

J Antimicrob Chemother. 2018 Jan 1;73(1):240-245. doi: 10.1093/jac/dkx369.

Abstract

Objectives: To evaluate data on outpatient antibiotic use in women post-labour as a potential method of monitoring infections in this group of patients.

Methods: Demographic and antibiotic prescription data originated from the registries of the National Health Fund (pol. Narodowy Fundusz Zdrowia). The measure of antibiotic use in this study was the percentage of women who purchased the drugs from prescriptions and DDDs.

Results: Among 67917 females who gave birth in the years 2013-14, 5050 (7.4%) purchased antibiotics prescribed by the obstetrician only. The average number of antibiotics bought per person was equivalent to ∼14 DDDs; in most cases (95.7%) these were β-lactams. Antibiotic use occurred significantly more frequently among younger patients (11.5% patients <18 years of age), those living in rural areas (8.2%) and those who underwent Caesarean section (8.1%). No significant differences were found between the reported day of labour and the post-partum use of antibiotics.

Conclusions: Antibiotic prescribing data can be used to verify/complement the information originating from hospital infection registries to monitor rates of infection in obstetric patients.

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / therapeutic use*
  • Cesarean Section / adverse effects
  • Drug Prescriptions / statistics & numerical data
  • Drug Utilization / statistics & numerical data*
  • Endometritis / drug therapy
  • Endometritis / epidemiology
  • Female
  • Humans
  • Infection Control / methods*
  • Mastitis / drug therapy
  • Mastitis / epidemiology
  • Obstetric Labor Complications / drug therapy*
  • Obstetric Labor Complications / epidemiology*
  • Obstetric Labor Complications / microbiology
  • Outpatients
  • Poland / epidemiology
  • Postpartum Period
  • Practice Patterns, Physicians'
  • Pregnancy
  • Respiratory Tract Infections / drug therapy
  • Respiratory Tract Infections / epidemiology
  • Urinary Tract Infections / drug therapy
  • Urinary Tract Infections / epidemiology
  • Young Adult

Substances

  • Anti-Bacterial Agents