Angioma serpiginosum is a rare dermal pathology characterized by pinpoint violaceous to coppery-red punctate maculopapular eruptions that cluster together in linear, serpiginous (ie, snake-like), or gyrate (ie, ring) patterns on an erythematous background. Angioma serpiginosum affects the lower limbs more commonly than other areas and is more frequently seen in females. The exact pathophysiology of this nevoid condition is not entirely known. Experts theorize that the condition may evolve from the proliferation of endothelial cells and the formation of new capillaries, not merely the dilation of preexisting capillaries.
Angioma serpiginosum is not associated with malignancy or physically debilitating symptoms, but the condition can have a significant psychological impact on patients due to perceived disfigurement of their appearance. The primary indication for treatment is the cosmetic concerns of the patient. Therefore, the ability to differentiate this dermatologic pathology from similar conditions and familiarity with available treatments is essential for clinicians to obtain because proper management of angioma serpiginosum involves tailoring therapy to the patient's needs.
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