Vitamin D Metabolism in Bariatric Surgery

Marlene Chakhtoura; Maya Rahme; Ghada El-Hajj Fuleihan

doi:10.1016/j.ecl.2017.07.006

Vitamin D Metabolism in Bariatric Surgery

Endocrinol Metab Clin North Am. 2017 Dec;46(4):947-982. doi: 10.1016/j.ecl.2017.07.006.

Authors

Marlene Chakhtoura¹, Maya Rahme², Ghada El-Hajj Fuleihan²

Affiliations

¹ Department of Internal Medicine, Division of Endocrinology, Calcium Metabolism and Osteoporosis Program, WHO Collaborating Center for Metabolic Bone Disorders, American University of Beirut Medical Center, Riad El Solh, Beirut, Lebanon. Electronic address: mc39@aub.edu.lb.
² Department of Internal Medicine, Division of Endocrinology, Calcium Metabolism and Osteoporosis Program, WHO Collaborating Center for Metabolic Bone Disorders, American University of Beirut Medical Center, Riad El Solh, Beirut, Lebanon.

PMID: 29080645
DOI: 10.1016/j.ecl.2017.07.006

Abstract

Hypovitaminosis D is common in obese patients and persists after roux-en-Y gastric bypass and sleeve gastrectomy. Several societies recommend screening for vitamin D deficiency before bariatric surgery, and replacement doses of 3000 IU/d and up to 50,000 IU 1 to 3 times per week, in case of deficiency, with periodic monitoring. These regimens are mostly based on expert opinion. Large trials are needed to assess the vitamin D dose response, by type of bariatric surgery, and evaluate the effect on surrogate markers of skeletal outcomes. Such data are essential to derive desirable vitamin D levels in this population.

Keywords: Bariatric surgery; Guidelines; Obesity; RYGB; SG; Vitamin D.

Publication types

Review

MeSH terms

Bariatric Surgery / adverse effects*
Humans
Postoperative Complications / blood
Vitamin D / analogs & derivatives*
Vitamin D / blood
Vitamin D Deficiency / blood
Vitamin D Deficiency / etiology*

Substances

Vitamin D
25-hydroxyvitamin D