Pt nanoparticles supported on nitrogen-doped porous graphene for sensitive detection of Tadalafil

Abdulwahab Salah; Mehboob Hassan; Jian Liu; Minghui Li; Xiangjie Bo; Jean Chrysostome Ndamanisha; Liping Guo

doi:10.1016/j.jcis.2017.10.022

Pt nanoparticles supported on nitrogen-doped porous graphene for sensitive detection of Tadalafil

J Colloid Interface Sci. 2018 Feb 15:512:379-388. doi: 10.1016/j.jcis.2017.10.022. Epub 2017 Oct 7.

Authors

Abdulwahab Salah¹, Mehboob Hassan¹, Jian Liu¹, Minghui Li², Xiangjie Bo³, Jean Chrysostome Ndamanisha⁴, Liping Guo⁵

Affiliations

¹ Key Laboratory of Nanobiosensing and Nanobioanalysis at University of Jilin Province, Department of Chemistry, Northeast Normal University, 5268 Renmin Street, Changchun, Jilin Province 130024, PR China.
² Agriculture Environmental Protection and Rural Energy Management Terminal Station of Jilin Province, PR China.
³ Key Laboratory of Nanobiosensing and Nanobioanalysis at University of Jilin Province, Department of Chemistry, Northeast Normal University, 5268 Renmin Street, Changchun, Jilin Province 130024, PR China. Electronic address: baoxj133@nenu.edu.cn.
⁴ Université du Burundi, Département de Chimie, B. P. 1550, 2 Avenue de l'UNESCO, Bujumbura, Burundi. Electronic address: jean-chrysostome.ndamanisha@ub.edu.bi.
⁵ Key Laboratory of Nanobiosensing and Nanobioanalysis at University of Jilin Province, Department of Chemistry, Northeast Normal University, 5268 Renmin Street, Changchun, Jilin Province 130024, PR China. Electronic address: guolp078@nenu.edu.cn.

PMID: 29080533
DOI: 10.1016/j.jcis.2017.10.022

Abstract

Graphene (GR) is one of the most promising candidates for utilization in the electroanalytical field because of its superior electrocatalytic activity, excellent electronic conductivity, and high chemical stability. However, the GR sheets usually tend to stack together with π-π interaction. The spontaneous stacking leads to the aggregation of the GR sheets and imposes a negative feedback in the surface area of the GR, which obviously limits its electrochemical application. In this study, nitrogen-doped porous GR (NPGR) with different pore sizes is prepared by using silica (SiO₂) as a template. The NPGR exhibits high surface area and porous structure, fulfilling the requirement for supporting materials. Being a support, the structural uniqueness and N dopants of NPGR facilitate the deposition of Pt nanoparticles (Pt NPs). The Pt NPs/NPGR composites integrate the structural properties of NPGR and catalytic properties of Pt NPs. A selective and sensitive electrochemical sensor was successfully developed for sensitive determination of Tadalafil (TAD), showing a concentration range of 1.30-488.9μM and limit of detection of 0.268μM.

Keywords: Nitrogen-doping; Porous graphene; Pt nanoparticles; Tadalafil.

MeSH terms

Biosensing Techniques*
Catalysis
Electrochemical Techniques
Graphite / chemistry*
Limit of Detection
Metal Nanoparticles / chemistry*
Nitrogen / chemistry*
Platinum / chemistry*
Porosity
Silicon Dioxide / chemistry*
Tadalafil / analysis*

Substances

Platinum
Tadalafil
Silicon Dioxide
Graphite
Nitrogen