Shuffled magnetization-prepared multicontrast rapid gradient-echo imaging

Magn Reson Med. 2018 Jan;79(1):62-70. doi: 10.1002/mrm.26986. Epub 2017 Oct 27.

Abstract

Purpose: To develop a novel acquisition and reconstruction method for magnetization-prepared 3-dimensional multicontrast rapid gradient-echo imaging, using Hankel matrix completion in combination with compressed sensing and parallel imaging.

Methods: A random k-space shuffling strategy was implemented in simulation and in vivo human experiments at 7 T for 3-dimensional inversion recovery, T2 /diffusion preparation, and magnetization transfer imaging. We combined compressed sensing, based on total variation and spatial-temporal low-rank regularizations, and parallel imaging with pixel-wise Hankel matrix completion, allowing the reconstruction of tens of multicontrast 3-dimensional images from 3- or 6-min scans.

Results: The simulation result showed that the proposed method can reconstruct signal-recovery curves in each voxel and was robust for typical in vivo signal-to-noise ratio with 16-times acceleration. In vivo studies achieved 4 to 24 times accelerations for inversion recovery, T2 /diffusion preparation, and magnetization transfer imaging. Furthermore, the contrast was improved by resolving pixel-wise signal-recovery curves after magnetization preparation.

Conclusions: The proposed method can improve acquisition efficiencies for magnetization-prepared MRI and tens of multicontrast 3-dimensional images could be recovered from a single scan. Furthermore, it was robust against noise, applicable for recovering multi-exponential signals, and did not require any previous knowledge of model parameters. Magn Reson Med 79:62-70, 2018. © 2017 International Society for Magnetic Resonance in Medicine.

Keywords: Hankel matrix; MP-RAGE; T2/diffusion preparation; magnetization transfer; high field; inversion recovery; magnetization-prepared rapid gradient echo; shuffled k-space.

MeSH terms

  • Algorithms
  • Brain / diagnostic imaging*
  • Brain Mapping / methods
  • Computer Simulation
  • Contrast Media / chemistry*
  • Data Compression / methods
  • Diffusion
  • Healthy Volunteers
  • Humans
  • Image Interpretation, Computer-Assisted / methods
  • Imaging, Three-Dimensional
  • Magnetics*
  • Models, Statistical
  • Prospective Studies
  • Retrospective Studies
  • Signal-To-Noise Ratio

Substances

  • Contrast Media