Mutations in the JAK/STAT pathway genes and activation of the pathway, a relevant finding in nodal Peripheral T-cell lymphoma

Br J Haematol. 2018 Nov;183(3):497-501. doi: 10.1111/bjh.14984. Epub 2017 Oct 26.
No abstract available

Keywords: PTCL; TFH; JAK/STAT; NF-KB; expression; mutation; prognosis.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Janus Kinases* / genetics
  • Janus Kinases* / metabolism
  • Lymphoma, T-Cell, Peripheral* / genetics
  • Lymphoma, T-Cell, Peripheral* / metabolism
  • Lymphoma, T-Cell, Peripheral* / pathology
  • Mutation*
  • Neoplasm Proteins* / genetics
  • Neoplasm Proteins* / metabolism
  • STAT Transcription Factors* / genetics
  • STAT Transcription Factors* / metabolism
  • Signal Transduction / genetics*

Substances

  • Neoplasm Proteins
  • STAT Transcription Factors
  • Janus Kinases