Stage effect of chronic kidney disease in erectile function

Int Braz J Urol. 2018 Jan-Feb;44(1):132-140. doi: 10.1590/S1677-5538.IBJU.2017.0228.

Abstract

Purpose: The study aims to assess the influence of the stage of chronic kidney disease and glomerular filtration rate on prevalence and degree of erectile dysfunction.

Materials and methods: This transversal study, conducted from May 2013 to December 2015, included patients with chronic kidney disease in conservative treatment, stages III/IV/V. Erectile dysfunction was evaluated by the International Index of Erectile Function. Data classically associated with erectile dysfunction were obtained by medical record review. Erectile dysfunction, degree of erectile dysfunction, and other main variables associated with erectile dysfunction were compared between patients with chronic kidney disease on conservative treatment stages III versus IV/V using the Chi-square test. The relationship between score of the International Index of Erectile Dysfunction and glomerular filtration rate was established by Pearson correlation coefficient.

Results: Two hundred and forty five patients with chronic kidney disease in con-servative treatment participated of the study. The prevalence of erectile dysfunction in patients with chronic kidney disease in stages IV/V was greater than in stage III. Glomerular filtration rate positively correlated with score of the International Index of Erectile Dysfunction.

Conclusions: The study suggests that chronic kidney disease progression (glomerular filtration rate decrease and advance in chronic kidney disease stages) worsen erectile function. Hypothetically, diagnosis and treatment of erectile dysfunction may be anticipated with the analysis of chronic kidney disease progression.

Keywords: Erectile Dysfunction; Kidney Failure, Chronic; Renal Insufficiency, Chronic.

MeSH terms

  • Aged
  • Brazil / epidemiology
  • Cross-Sectional Studies
  • Disease Progression
  • Erectile Dysfunction / diagnosis
  • Erectile Dysfunction / epidemiology
  • Erectile Dysfunction / etiology*
  • Glomerular Filtration Rate
  • Humans
  • Kidney Failure, Chronic / complications*
  • Male
  • Middle Aged
  • Prevalence
  • Severity of Illness Index