Metastases of Hepatocellular Carcinoma Misdiagnosed as Isolated Hypertrophic Cardiomyopathy

Ann Hepatol. 2017;16(6):966-969. doi: 10.5604/01.3001.0010.5289.

Abstract

At present, cardiac metastasis of hepatocellular carcinoma is rarely mentioned in the literature. We report a hepatocellular carcinoma patient with cardiac metastasis misdiagnosed as hypertrophic cardiomyopathy in 2011. Two years later, on presentation of syncope, an abnormal ventricular septal size was recorded by ultrasound scan, and was subsequently shown by magnetic resonance imaging to be a tumour lesion. A myocardial biopsy confirmed infiltration of hepatocellular carcinoma. This observation underlines the risk of hepatocellular carcinoma cardiac metastasis, manifested in its infiltrative form as hypertrophic cardiomyopathy. In conclusion, we suggest that the ultrasound appearance of hypertrophic cardiomyopathy in hepatocellular carcinoma patients should be seen as a "red flag" and recommend the introduction of magnetic resonance imaging assessment of transplant candidates.

Keywords: Cardiac Metastasis. Echocardiography. Magnetic Resonance Imaging. CT scan..

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Carcinoma, Hepatocellular / diagnostic imaging
  • Carcinoma, Hepatocellular / secondary*
  • Carcinoma, Hepatocellular / therapy
  • Cardiomyopathy, Hypertrophic / diagnosis*
  • Diagnostic Errors*
  • Echocardiography
  • Heart Neoplasms / diagnostic imaging
  • Heart Neoplasms / secondary*
  • Heart Neoplasms / therapy
  • Humans
  • Liver Neoplasms / diagnostic imaging
  • Liver Neoplasms / pathology*
  • Liver Neoplasms / therapy
  • Magnetic Resonance Imaging
  • Middle Aged
  • Palliative Care
  • Predictive Value of Tests
  • Tomography, X-Ray Computed