Epidemiology and Risk Factors of Uterine Fibroids

Dora Pavone; Sara Clemenza; Flavia Sorbi; Massimiliano Fambrini; Felice Petraglia

doi:10.1016/j.bpobgyn.2017.09.004

Epidemiology and Risk Factors of Uterine Fibroids

Best Pract Res Clin Obstet Gynaecol. 2018 Jan:46:3-11. doi: 10.1016/j.bpobgyn.2017.09.004. Epub 2017 Oct 1.

Authors

Dora Pavone¹, Sara Clemenza¹, Flavia Sorbi¹, Massimiliano Fambrini¹, Felice Petraglia²

Affiliations

¹ Department of Biomedical, Experimental and Clinical Sciences, Division of Obstetrics and Gynecology, University of Florence, Florence, Italy.
² Department of Biomedical, Experimental and Clinical Sciences, Division of Obstetrics and Gynecology, University of Florence, Florence, Italy. Electronic address: felice.petraglia@unifi.it.

PMID: 29054502
DOI: 10.1016/j.bpobgyn.2017.09.004

Abstract

Risk factors, both modifiable and non-modifiable, are associated with the development of fibroids. These include age, race, endogenous and exogenous hormonal factors, obesity, uterine infection, and lifestyle (diet, caffeine and alcohol consumption, physical activity, stress, and smoking). Some of the epidemiological data were conflicting; consequently, further studies are needed to better understand the factors that influence fibroid prevalence.

Keywords: Epidemiology; Genetic factors; Lifestyle; Reproductive history; Risk factor; Uterine fibroids.

Publication types

Review

MeSH terms

Age Factors
Black People / statistics & numerical data
Female
Humans
Leiomyoma / epidemiology*
Leiomyoma / etiology*
Leiomyoma / genetics
Prevalence
Risk Factors
Uterine Neoplasms / epidemiology*
Uterine Neoplasms / etiology*
Uterine Neoplasms / genetics
White People / statistics & numerical data