Automatic selection of localized region-based active contour models using image content analysis applied to brain tumor segmentation

Comput Biol Med. 2017 Dec 1:91:69-79. doi: 10.1016/j.compbiomed.2017.10.003. Epub 2017 Oct 7.

Abstract

Brain tumor segmentation is a routine process in a clinical setting and provides useful information for diagnosis and treatment planning. Manual segmentation, performed by physicians or radiologists, is a time-consuming task due to the large quantity of medical data generated presently. Hence, automatic segmentation methods are needed, and several approaches have been introduced in recent years including the Localized Region-based Active Contour Model (LRACM). There are many popular LRACM, but each of them presents strong and weak points. In this paper, the automatic selection of LRACM based on image content and its application on brain tumor segmentation is presented. Thereby, a framework to select one of three LRACM, i.e., Local Gaussian Distribution Fitting (LGDF), localized Chan-Vese (C-V) and Localized Active Contour Model with Background Intensity Compensation (LACM-BIC), is proposed. Twelve visual features are extracted to properly select the method that may process a given input image. The system is based on a supervised approach. Applied specifically to Magnetic Resonance Imaging (MRI) images, the experiments showed that the proposed system is able to correctly select the suitable LRACM to handle a specific image. Consequently, the selection framework achieves better accuracy performance than the three LRACM separately.

Keywords: 00-01; 99-00; Active contours; Automatic feature selection; Brain tumor segmentation; Image content.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Brain / diagnostic imaging*
  • Brain Neoplasms / diagnostic imaging*
  • Humans
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods*