Severe granulocytic dysplasia with vacuolar rosettes in a myelodysplastic syndrome with low-copy KMT2A gain

Br J Haematol. 2018 Feb;180(3):320. doi: 10.1111/bjh.14964. Epub 2017 Oct 19.

Authors

Eduardo Rodríguez-Arbolí¹, Rosario M Morales-Camacho¹, Concepción Prats-Martín¹, María Teresa Vargas¹, María Isabel Montero¹, Ricardo Bernal¹

Affiliation

¹ UGC de Hematología. Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS)/CSIC/Universidad de Sevilla, Sevilla, Spain.

PMID: 29048106
DOI: 10.1111/bjh.14964

No abstract available

Publication types

Case Reports

MeSH terms

Adult
Blood Cell Count
Bone Marrow / pathology
DNA Copy Number Variations*
Fatal Outcome
Female
Granulocytes / pathology*
Histone-Lysine N-Methyltransferase / genetics*
Humans
In Situ Hybridization, Fluorescence
Karyotyping
Myelodysplastic Syndromes / diagnosis*
Myelodysplastic Syndromes / drug therapy
Myelodysplastic Syndromes / genetics*
Myeloid-Lymphoid Leukemia Protein / genetics*

Substances

KMT2A protein, human
Myeloid-Lymphoid Leukemia Protein
Histone-Lysine N-Methyltransferase