Double C-S bond formation via C-H bond functionalization: synthesis of benzothiazoles and naphtho[2,1-d]thiazoles from N-substituted arylamines and elemental sulfur

Xiaoming Zhu; Yuzhong Yang; Genhua Xiao; Jianxin Song; Yun Liang; Guobo Deng

doi:10.1039/c7cc07366f

Double C-S bond formation via C-H bond functionalization: synthesis of benzothiazoles and naphtho[2,1-d]thiazoles from N-substituted arylamines and elemental sulfur

Chem Commun (Camb). 2017 Oct 31;53(87):11917-11920. doi: 10.1039/c7cc07366f.

Authors

Xiaoming Zhu¹, Yuzhong Yang, Genhua Xiao, Jianxin Song, Yun Liang, Guobo Deng

Affiliation

¹ National & Local Joint Engineering Laboratory for New Petro-chemical Materials and Fine Utilization of Resources, Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research, Ministry of Education, Key Laboratory of the Assembly and Application of Organic Functional Molecules, Hunan Normal University, Changsha, Hunan 410081, China. yliang@hunnu.edu.cn gbdeng@hunnu.edu.cn.

PMID: 29044251
DOI: 10.1039/c7cc07366f

Abstract

A novel, atom economic, and environmentally friendly method for the synthesis of 2-substituted benzothiazoles and 2-substituted naphtho[2,1-d]thiazoles from N-substituted arylamines and elemental sulfur has been developed under metal-free conditions. The reaction underwent the process of double C-S bond formation through C-H bond functionalization.