Brugada phenocopy caused by a compressive mediastinal tumor

Ann Noninvasive Electrocardiol. 2018 May;23(3):e12509. doi: 10.1111/anec.12509. Epub 2017 Oct 15.

Abstract

Recently, it has been shown that even experts in electrocardiography cannot differentiate the electrocardiographic pattern of genuine Brugada syndrome (BrS) from Brugada phenocopy (BrP). For this reason, this differentiation depends on the presence of established criteria both for BrS and BrP. In this manuscript, we present a patient with type 1 Brugada electrocardiographic pattern caused by expansive anterior mediastinal non-Hodgkin's lymphoma (NHL) with mechanical compression on the right ventricular outflow tract. The electrocardiographic pattern disappeared rapidly after antineoplastic measures.

Keywords: Brugada phenocopy; Brugada syndrome; non-Hodgkin's lymphoma; sodium channel blocker.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Brugada Syndrome / diagnosis
  • Brugada Syndrome / etiology*
  • Diagnosis, Differential
  • Electrocardiography
  • Female
  • Humans
  • Mediastinal Neoplasms / complications*
  • Mediastinal Neoplasms / diagnostic imaging
  • Phenotype
  • Tomography, X-Ray Computed