The Association between CHA2DS2-VASc Score and Mortality in Patients with Heart Failure with Reduced Ejection Fraction

Orkun Temizer; Burak Açar; Çağrı Yayla; Sefa Ünal; Ahmet Göktuğ Ertem; Esra Gücük İpek; Uğur Canpolat; Bihter Şentürk; Hatice Selçuk; Timur Selçuk

doi:10.6515/acs20170221a

The Association between CHA₂DS₂-VASc Score and Mortality in Patients with Heart Failure with Reduced Ejection Fraction

Acta Cardiol Sin. 2017 Jul;33(4):429-435. doi: 10.6515/acs20170221a.

Affiliation

¹ Türkiye Yüksek Ihtisas Training and Research Hospital, Cardiology Clinic, Ankara, Turkey.

Abstract

Background: Heart failure (HF) is associated with significant mortality and morbidity. Therefore, identifying high-risk patients may optimize treatment for HF patients and reduce adverse events. The aim of this study was to assess the role of the CHA₂DS_2-VASc score to predict mortality in patients with reduced left ventricular ejection fraction (LVEF).

Methods: A total of 106 patients with reduced LVEF were enrolled in this study. All patients completed a one-year follow-up, and a CHA₂DS₂-VASc score was calculated for each patient.

Results: Twenty-one patients (19.8%) died during the 1-year follow-up. We found that baseline functional status, CHA₂DS₂-VASc score, brain natriuretic peptide, blood urea and hemoglobin levels were associated with mortality. In the multivariate analysis, CHA₂DS₂-VASc score and functional capacity were the only predictors of 1-year mortality.

Conclusions: Use of the CHA₂DS₂-VASc score appears to be feasible for risk stratification and mortality prediction in patients with reduced LVEF.

Keywords: CHA2DS2-VASc score; Heart failure; Mortality.