A neuropsychologist's view: Outcome after RF-ablation for mTLE

Epilepsy Res. 2018 May:142:167-169. doi: 10.1016/j.eplepsyres.2017.10.007. Epub 2017 Oct 6.

Abstract

Concern about postoperative worsening of cognitive functions after temporal lobe epilepsy surgery is an important issue. In this article we review our data on neuropsychological outcome after radiofrequency (RF) ablation of amygdalohippocampal complex (AHC). On a group level we found initial improvement in intelligence domains and unchanged memory scores one year after the surgery. During longitudinal follow-up, we found improvement in both intellectual and memory domains. This improvement was most pronounced up to two years after surgery. On an individual level, no patient worsened in any intellectual domain and most patients improved in memory. We hypothesize that this favorable outcome may be a consequence of minimization of collateral damage and incomplete destruction of target structures. We also summarize our experience with psychiatric complications of the procedure.

Keywords: Intelligence; Memory; Neuropsychological assessment; Stereotactic amygdalohippocampectomy; WADA test.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amygdala / surgery
  • Epilepsy, Temporal Lobe / complications*
  • Epilepsy, Temporal Lobe / surgery*
  • Hippocampus / surgery
  • Humans
  • Intellectual Disability / etiology*
  • Intellectual Disability / surgery
  • Memory Disorders / etiology*
  • Memory Disorders / surgery
  • Neuropsychological Tests
  • Radiofrequency Ablation / methods*
  • Treatment Outcome*