Diagnostics of paraneoplastic neurological syndromes

Neurol Sci. 2017 Oct;38(Suppl 2):237-242. doi: 10.1007/s10072-017-3031-5.

Abstract

This document presents the guidelines for onconeural antibody testing that have been developed following a consensus process built on questionnaire-based surveys, internet contacts, and discussions at workshops of the sponsoring Italian Association of Neuroimmunology (AINI) congresses. Essential clinical information on paraneoplastic neurological syndromes, indications and limits of onconeural antibody testing, instructions for result interpretation, and an agreed laboratory protocol (Appendix) are reported for the communicative community of neurologists and clinical pathologists.

Keywords: Laboratory diagnostics; Neurological autoimmune diseases; Onconeural antibodies.

Publication types

  • Review

MeSH terms

  • Autoantibodies / immunology
  • Autoantibodies / metabolism
  • Humans
  • Paraneoplastic Syndromes, Nervous System / diagnosis*
  • Paraneoplastic Syndromes, Nervous System / immunology
  • Paraneoplastic Syndromes, Nervous System / metabolism

Substances

  • Autoantibodies