Construction of biological hybrid microcapsules with defined permeability towards programmed release of biomacromolecules

Lina Liu; Dongyue Su; Xiaoman Liu; Lei Wang; Jie Zhan; Hui Xie; Xianghe Meng; Hao Zhang; Jian Liu; Xin Huang

doi:10.1039/c7cc06243e

Construction of biological hybrid microcapsules with defined permeability towards programmed release of biomacromolecules

Chem Commun (Camb). 2017 Oct 24;53(85):11678-11681. doi: 10.1039/c7cc06243e.

Authors

Lina Liu¹, Dongyue Su, Xiaoman Liu, Lei Wang, Jie Zhan, Hui Xie, Xianghe Meng, Hao Zhang, Jian Liu, Xin Huang

Affiliation

¹ MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, Key Laboratory of Microsystems and Microstructures Manufacturing Ministry of Education, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, 150001, P. R. China. liuxiaoman@hit.edu.cn xinhuang@hit.edu.cn.

PMID: 29019357
DOI: 10.1039/c7cc06243e

Abstract

An effective method to modulate the permeability of microcapsules on demand based on a "self-sacrificing" strategy was demonstrated, which then realized a programmed release of the corresponding loaded biomacromolecules.

MeSH terms

Animals
Capsules / chemistry*
Cattle
DNA / chemistry
Dextrans / chemistry*
Drug Liberation
Muramidase / chemistry*
Permeability
Porosity
Serum Albumin, Bovine / chemistry*

Substances

Capsules
Dextrans
Serum Albumin, Bovine
DNA
Muramidase