Sub-internal limiting membrane hemorrhage treated with intravitreal tissue plasminogen activator followed by octafluoropropane gas injection

Yu-Kang Chou; Yi-Ming Huang; Po-Kang Lin

doi:10.1016/j.tjo.2014.10.006

Sub-internal limiting membrane hemorrhage treated with intravitreal tissue plasminogen activator followed by octafluoropropane gas injection

Taiwan J Ophthalmol. 2015 Oct-Dec;5(4):198-201. doi: 10.1016/j.tjo.2014.10.006. Epub 2014 Dec 4.

Authors

Yu-Kang Chou^{1

2}, Yi-Ming Huang², Po-Kang Lin^{1

2}

Affiliations

¹ Medical Department, National Yang-Ming University, Taipei, Taiwan.
² Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.

Abstract

Sub-internal limiting membrane (sub-ILM) hemorrhage is a relatively rare disease which is associated with different etiologies and often leads to loss of visual acuity. We report two cases of sub-ILM hemorrhage, both confirmed by optical coherence tomography (OCT) and treated with an intravitreal injection of tissue plasminogen activator (tPA) followed by an octafluoropropane (C₃F₈) pneumopexy and a strict postoperative prone positioning. The hemorrhage was totally resolved and complete visual recovery was achieved in both cases. We found tPA hemolysis with C₃F₈ pneumopexy to be a safe and effective method for treating sub-ILM hemorrhage.

Keywords: octafluoropropane; sub-internal limiting membrane hemorrhage; tissue plasminogen activator.

Publication types

Case Reports