Real-time ultrasound-guided axillary vein cannulation in children: a randomised controlled trial

Anaesthesia. 2017 Dec;72(12):1516-1522. doi: 10.1111/anae.14086. Epub 2017 Oct 9.

Abstract

The axillary vein is a good site for ultrasound-guided central venous cannulation in terms of infection rate, patient comfort and its anatomical relationship with the clavicle and lungs. We compared real-time ultrasound-guided axillary vein cannulation with conventional infraclavicular landmark-guided subclavian vein cannulation in children. A total of 132 paediatric patients were randomly allocated to either ultrasound-guided axillary vein (axillary group) or landmark-guided subclavian vein (landmark group). The outcomes measured were success rate after two attempts, first-attempt success rate, time to cannulation and complication rate. The success rate after two attempts was 83% in the axillary group compared with 63% in the landmark group (odds ratio 2.85, 95%CI 1.25-6.48, p = 0.010). The first-attempt success rate was 46% for the axillary group and 40% for the landmark group (p = 0.274) and median time to cannulation was 156 s for the axillary group and 180 s for the landmark group (p = 0.286). There were no differences in complication rates between the two groups, although three episodes of subclavian artery puncture occurred in the landmark group (p = 0.08). We conclude that axillary vein cannulation using a real-time ultrasound-guided in-plane technique is useful and effective in paediatric patients.

Keywords: axillary vein; central venous cannulation; paediatric; ultrasound.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Axillary Vein / diagnostic imaging*
  • Catheterization, Central Venous / methods*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Male
  • Prospective Studies
  • Ultrasonography, Interventional / methods*