A model of an inflammatory bowel disease population-based registry: The Forlì experience (1993-2013)

Dig Liver Dis. 2018 Jan;50(1):32-36. doi: 10.1016/j.dld.2017.09.120. Epub 2017 Sep 21.

Abstract

Background and aims: The article presents a population-based registry designed to estimate incidence and prevalence of inflammatory bowel disease (IBD) in the area of Forlì (north-eastern Italy).

Methods: The registry included all patients with IBD ulcerative colitis (UC) and Crohn's disease (CD) in the Forlì area from 1993 to 2013. A data manager matched records from various sources.

Results: Seven hundred ninety-one patients were registered during the study period, 564 (71.3%) with UC and 227 (28.7%) with CD. The standardized annual incidence rate for UC was 12.8 per 100,000 females (95% CI 11.1-14.4) and 15.7 per 100,000 males (95% CI 13.9-17.5). That of CD was 7.0 per 100,000 for females (95% CI 5.7-8.3) and 5.4 per 100,000 males (95% CI 4.3-6.4). The prevalence of CD and UC on 1 January 2014 was 109.2 per 100,000 inhabitants (95% CI 94.3-124.2) and 266.4 per 100,000 inhabitants (95% CI 243.4-289.7), respectively.

Conclusions: Although further studies are needed, the data suggest that incidence and prevalence of IBD in Italy are underestimated.

Keywords: Crohn’s disease; Incidence; Population-based registry; Prevalence; Ulcerative colitis.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Colitis, Ulcerative / epidemiology*
  • Crohn Disease / epidemiology*
  • Female
  • Forecasting*
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Prevalence
  • Registries*
  • Sex Distribution
  • Young Adult