Perspectives on medicinal properties of natural phenolic monoterpenoids and their hybrids

Mol Divers. 2018 Feb;22(1):225-245. doi: 10.1007/s11030-017-9787-y. Epub 2017 Oct 7.

Abstract

Carvacrol, thymol and eugenol belong to a class of naturally presenting phenols with a ten-carbon unit, which are present in essential oils of many plants. These versatile molecules are incorporated as useful ingredients in many food products and find applications in agricultural, pharmaceutical, fragrance, cosmetic, flavor and other industries. They are wide ranging of biological and pharmaceutical activities: anti-inflammatory, antimicrobial, analgesic, anticancer and antioxidant. This review summarizes pharmacological and medicinal activities of these phytochemicals and their synthetic hybrids.

Keywords: Carvacrol; Essential oils; Eugenol; Pharmacological and medicinal activities; Thymol.

Publication types

  • Review

MeSH terms

  • Allosteric Regulation
  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / pharmacology
  • Anti-Infective Agents / therapeutic use
  • Biological Products / chemistry*
  • Biological Products / pharmacology*
  • Biological Products / therapeutic use
  • Humans
  • Molecular Structure
  • Monoterpenes / chemistry*
  • Monoterpenes / pharmacology*
  • Monoterpenes / therapeutic use
  • Phenols / chemistry*
  • Phenols / pharmacology*
  • Phenols / therapeutic use
  • Phytochemicals / chemistry
  • Phytochemicals / pharmacology
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology

Substances

  • Anti-Infective Agents
  • Biological Products
  • Monoterpenes
  • Phenols
  • Phytochemicals
  • Plant Extracts