Slowing Down Aging

Cell Metab. 2017 Oct 3;26(4):592-593. doi: 10.1016/j.cmet.2017.09.012.

Abstract

The hypothalamus plays a key role in coordinating the physiological changes that underlie mammalian aging. In a recent issue of Nature, Cai and colleagues (2017) shed new light on the mechanism of this effect by providing evidence that hypothalamic stem cells may regulate aging through the release of microRNAs in exosomes.

MeSH terms

  • Aging*
  • Animals
  • Exosomes / metabolism
  • Humans
  • Hypothalamus / cytology
  • Hypothalamus / physiology*
  • MicroRNAs / metabolism*
  • NF-kappa B / metabolism
  • Neural Stem Cells / metabolism*
  • Signal Transduction
  • Stress, Physiological

Substances

  • MicroRNAs
  • NF-kappa B