The prognostic impact of distal anastomotic new entry after acute type I aortic dissection repair

Eur J Cardiothorac Surg. 2017 Nov 1;52(5):867-873. doi: 10.1093/ejcts/ezx223.

Abstract

Objectives: Distal anastomotic new entry (DANE) is considered to be one of the causes of patent false lumen (PFL) after acute type I aortic dissection repair. However, there have been few articles with regard to this important issue. We assessed the influence of PFL caused by DANE on long-term outcomes.

Methods: One hundred twenty-two patients underwent emergency surgery for acute type I aortic dissection (2007-12). The in-hospital mortality was 8% (10 patients). Among the survivors, 93 patients (mean age 67 years) underwent enhanced computed tomography within 2 weeks after the operation. These patients were divided into 3 groups according to the status of the residual FL: those with a PFL with DANE (n = 19) or without DANE (n = 27) and those with a thrombosed FL (n = 47). Changes in descending aortic diameter were analysed between early and last follow-up images.

Results: Aortic growth rate in the PFL with DANE group was greater than that of the other 2 groups (P < 0.05). The PFL with DANE group demonstrated a lower rate of freedom from dissection-related event of distal aorta (66% at 5 years) and enlargement of distal aortic lesions (62% at 5 years). There were no significant differences in late survival among the groups. PFL with DANE was one of the significant risk factors for distal aortic events.

Conclusions: PFL caused by DANE after acute type I aortic dissection repair showed greater aortic growth rate of the descending aorta and was one of the significant risk factors for distal aortic events.

Keywords: Aortic dissection.

MeSH terms

  • Aged
  • Aorta / surgery
  • Aortic Aneurysm, Thoracic / mortality
  • Aortic Aneurysm, Thoracic / surgery*
  • Aortic Dissection / mortality
  • Aortic Dissection / surgery*
  • Blood Vessel Prosthesis Implantation / adverse effects*
  • Blood Vessel Prosthesis Implantation / statistics & numerical data*
  • Female
  • Hospital Mortality
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Prognosis
  • Retrospective Studies
  • Risk Factors