Hidden FLT3-D835Y clone in FLT3-ITD-positive acute myeloid leukemia that evolved into very late relapse with T-lymphoblastic leukemia

Leuk Lymphoma. 2018 Jun;59(6):1490-1493. doi: 10.1080/10428194.2017.1382696. Epub 2017 Oct 3.

Authors

Affiliations

¹ a Department of Hematology , Tokyo Medical University , Tokyo , Japan.
² b Department of Molecular Oncology , Institute of Medical Science, Tokyo Medical University , Tokyo , Japan.
³ c Department of Pathology and Tumor Biology , Kyoto University , Kyoto , Japan.
⁴ d Laboratory of DNA Information Analysis , Human Genome Center, Institute of Medical Science, The University of Tokyo , Tokyo , Japan.

PMID: 28972800
DOI: 10.1080/10428194.2017.1382696

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Biomarkers
Bone Marrow Transplantation
Cytogenetic Analysis
Disease Progression
Gene Duplication
Humans
Leukemia, Myeloid, Acute / genetics*
Leukemia, Myeloid, Acute / pathology*
Leukemia, Myeloid, Acute / therapy
Male
Middle Aged
Mutation
Neoplasms, Second Primary / diagnosis*
Neoplasms, Second Primary / etiology*
Neoplasms, Second Primary / therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / etiology*
Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy
Treatment Outcome
fms-Like Tyrosine Kinase 3 / genetics*

Substances

Biomarkers
fms-Like Tyrosine Kinase 3