The article presents data relating to structural changes in rat adenohypophysis in experimental burn disease and its treatment. Experimental studies were conducted for defining peculiarities of structural changes in rats' adenohypophisis without and after skin burn injuries (in 7-14 and 21-30 days) alongside its correction with 0.9% NaCl solution. Application of DNA-cytometry allowed defining subtle mechanisms of pathogenic influence of burn injuries on the organism in general and the cells in particular.